If you keep changing gears, you can basically use the information they have in front of them against them.
I think when people use this type of software they start to rely on them far more heavily than everything else (betting patterns, timing tells) etc.
Also, I think it results in them stop taking notes, as if these stats are "all they need". But this leads them to stop thinking about what a player has when he calls in the BB and check raises Ace high boards, how much they raise with good hands in comparision to weak hands etc etc.
So, if they are going to OVERUSE this software, you playing a natural game where you pay more attention to the more important information, you may actually have the edge.
If you run it and it says they have VPIP of 40%, u really won't see this anyway urself? Although I admit it can be very useful when multitabling a lot of tables, but again, you don't really need it at the low limits as ABC yields profit anyway, and the players higher up keep changing gears anyway?
EDIT: This is not a rant, I have just read it and it seems a bit rambly. I was basically just typing my thoughts as I was thinking them